{"id":4636,"date":"2024-02-20T20:39:15","date_gmt":"2024-02-20T20:39:15","guid":{"rendered":"https:\/\/seniorfitness.blog\/?p=4636"},"modified":"2024-02-19T20:40:56","modified_gmt":"2024-02-19T20:40:56","slug":"blodanalyse-til-paavisning-af-fremtidig-udvikling-af-demens","status":"publish","type":"post","link":"https:\/\/seniorfitness.blog\/?p=4636","title":{"rendered":"Blodanalyse til p\u00e5visning af fremtidig udvikling af demens"},"content":{"rendered":"

En nyhedsartikel p\u00e5 TV2 nyheder den 15. februar bedyrer at “Ny blodpr\u00f8ve kan forudsige demens med 90 procent sikkerhed – men \u00f8nsker du den viden?<\/em><\/a>”<\/p>\n

Det videnskabelige arbejde, der ligger til baggrund for artiklen blev udgivet i Nature Aging<\/a> den 12. februar.<\/p>\n

Mere specifikt var det kombinationen af status for 4 proteiner sammen med andre konventionelle risikofaktorer som alder, k\u00f8n, uddannelsesniveau og en genetisk faktor (APOE epsilon 4). Til sammen gav det en estimeret 90% pr\u00e6cision ift. at forudsige udvikling af demens mindst 10 \u00e5r f\u00f8r den kliniske diagnose kan stilles. De 4 proteiner er GFAP, NEFL, GDF15 og LTB2. Eksempelvis har personer med forh\u00f8jede niveauer af GFAP en dobbelt s\u00e5 h\u00f8j risiko for at udvikle demens som de der har lavere niveauer i blodet.<\/p>\n

Artiklen p\u00e5 TV2 nyheder henviser ogs\u00e5 til professor Gunhild Waldemar fra Nationalt Videnscenter for Demens, som udtaler, at eksisterende metoder; PET scanning eller unders\u00f8gelse af cerobrospinalv\u00e6ske kan afsl\u00f8re sygdomstegn op til 20 \u00e5r f\u00f8r man bliver ramt. Disse tiltag er dog mere omfattende og dyrere end en simpel blodpr\u00f8ve. Der er dog endnu ikke en blodpr\u00f8ve-test klar til brug i klinikken.<\/p>\n

Det er nok v\u00e6rd at bem\u00e6rke, at hverken negativ resultat ved blodtest, PET scanning eller en lumbalpunktur kan udelukke, at man udvikler demens i fremtiden.<\/p>\n

Det er formentlig blot et sp\u00f8rgsm\u00e5l om tid f\u00f8r s\u00e5dan en test bliver tilg\u00e6ngelig – og det vil nok s\u00e6tte nogle etiske diskussioner i gang. Diskussionen kunne s\u00e5dan set allerede v\u00e6re startet for det er allerede muligt at tage en simpel gentest, hvis man vil vide om man er i \u00f8get risiko for at udvikle Alzheimers. Jeg har ikke facttjekket om tallene er helt pr\u00e6cise, men p\u00e5 mediet STAT<\/a> vil typisk 1 ud\u00a0 af 10 \u00e6ldre udvikle Alzheimers. Hvis man b\u00e6rer \u00e9n APOE e4 allel af APOE genet \u00f8ges risikoen trefold; er begge APOE alleler af APOE e4 typen \u00f8ges risikoen omkring 12 gange.<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

En nyhedsartikel p\u00e5 TV2 nyheder den 15. februar bedyrer at “Ny blodpr\u00f8ve kan forudsige demens med 90 procent sikkerhed – men \u00f8nsker du den viden?” […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":4640,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[448],"tags":[31,765,29,764],"class_list":["post-4636","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mentalt-helbred","tag-alzheimers","tag-apoe","tag-demens","tag-gfap"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/seniorfitness.blog\/wp-content\/uploads\/2024\/02\/2024-02-old-peoples-home-63615_1280.jpg?fit=1280%2C960&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p8lpEz-1cM","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/4636","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4636"}],"version-history":[{"count":5,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/4636\/revisions"}],"predecessor-version":[{"id":4643,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/4636\/revisions\/4643"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/media\/4640"}],"wp:attachment":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4636"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4636"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4636"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}