{"id":4782,"date":"2024-05-31T21:25:53","date_gmt":"2024-05-31T21:25:53","guid":{"rendered":"https:\/\/seniorfitness.blog\/?p=4782"},"modified":"2024-05-31T21:25:53","modified_gmt":"2024-05-31T21:25:53","slug":"stoffer-der-bremser-udvikling-af-alzheimers-hos-mus","status":"publish","type":"post","link":"https:\/\/seniorfitness.blog\/?p=4782","title":{"rendered":"Stoffer der bremser udvikling af Alzheimers – hos mus"},"content":{"rendered":"

Det er n\u00e6ppe n\u00f8dvendigt at fremh\u00e6ve, at videnskabelige resultater baseret p\u00e5 studier p\u00e5 fors\u00f8gsdyr skal tolkes med forbehold, hvis man \u00f8nsker at overf\u00f8re til mennesker. Men trods alt er der ogs\u00e5 mange lighedspunkter mellem pattedyr, selv fra mus til mennesker.<\/p>\n

S\u00e6rligt inden for forskning i demens-sygdomme er der brug for et gennembrud, s\u00e5 her kan dyremodeller levere nogle hurtigere fremkommelige resultater, som man s\u00e5 efterf\u00f8lgende kan fors\u00f8ge at eftervise hos mennesker.<\/p>\n

Et relativt nyt musestudie<\/a> har p\u00e5vist, at for mus med Alzheimers, som blev udsat for at inhalere menthol, s\u00e5 blev deres kognitive forfald bremset. Forskerne har tilskrevet, at det kunne have en sammenh\u00e6ng med p\u00e5virkning af immunsystemet. Mere specifikt fandt de en reduktion af interleukin-1-beta, et signalstof, der er involveret i stimulering af inflammation, s\u00e6rligt bestemte T-celler.<\/p>\n

“…surprisingly, we observed that short exposures to this substance for six months prevented cognitive decline in the mice with Alzheimer’s and, what is most interesting, also improved the cognitive ability of healthy young mice.” Juan Jos\u00e9 Lasarte fra Center for Applied Medical Research til science-alert<\/a>.<\/p><\/blockquote>\n

Endnu et studie<\/a> baseret p\u00e5 mus har afsl\u00f8ret et stof, der m\u00e5ske kan give en hj\u00e6lpende h\u00e5nd til udvikling af behandling, som kan forsinke udviklingen af Alzheimers.<\/p>\n

Forskere fra K\u00f8benhavns Universitet<\/a> har testet Urolithin A p\u00e5 fors\u00f8gsmus med Alzheimers. Forskerne fandt bedringer i forhold til indl\u00e6ring, hukommelse og lugtesans – og kunne se metabolske effekter inde i cellerne, bl.a. en bedre evne til at \u201crydde op\u201d.<\/p>\n

Urolithin A er et stof, der dannes af tarmbakterier ved oms\u00e6tning af ellagitaniner, der naturligt forekommer i fx granat\u00e6bler, bromb\u00e6r, jordb\u00e6r og valn\u00f8dder.<\/p>\n

Sp\u00f8rgsm\u00e5let er om det er stoffer, som ogs\u00e5 virker p\u00e5 mennesker. Og hvis de g\u00f8r, kan det lede til en st\u00f8rre forst\u00e5else for de mekanismer, der f\u00f8rer til udvikling af Alzheimers?<\/p>\n

 <\/p>\n","protected":false},"excerpt":{"rendered":"

Det er n\u00e6ppe n\u00f8dvendigt at fremh\u00e6ve, at videnskabelige resultater baseret p\u00e5 studier p\u00e5 fors\u00f8gsdyr skal tolkes med forbehold, hvis man \u00f8nsker at overf\u00f8re til mennesker. […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":4786,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[448],"tags":[31,793,790,791,792,789],"class_list":["post-4782","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-mentalt-helbred","tag-alzheimers","tag-dyreforsoeg","tag-ellagitanin","tag-interleukin","tag-museforsoeg","tag-urolithin"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/seniorfitness.blog\/wp-content\/uploads\/2024\/05\/candies-2549410_1280.jpg?fit=1280%2C929&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p8lpEz-1f8","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/4782","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4782"}],"version-history":[{"count":4,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/4782\/revisions"}],"predecessor-version":[{"id":4787,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/4782\/revisions\/4787"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/media\/4786"}],"wp:attachment":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4782"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4782"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4782"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}