{"id":5051,"date":"2025-12-23T23:35:06","date_gmt":"2025-12-23T23:35:06","guid":{"rendered":"https:\/\/seniorfitness.blog\/?p=5051"},"modified":"2025-12-23T23:35:06","modified_gmt":"2025-12-23T23:35:06","slug":"c-reaktivt-protein-og-risiko-for-hjerte-kar-sygdom","status":"publish","type":"post","link":"https:\/\/seniorfitness.blog\/?p=5051","title":{"rendered":"C-reaktivt protein og risiko for hjerte-kar sygdom"},"content":{"rendered":"

Som det bl.a. kan l\u00e6ses i et tidligere indl\u00e6g<\/a> her p\u00e5 bloggen s\u00e5 er der stadig diskussioner om, hvor betydende kolesteroltallet er i forhold til risikoen for at udvikle hjerte-kar sygdom.<\/p>\n

I nogle kredse argumenteres der for, at en blodm\u00e5ling med et h\u00f8jt kolesteroltal ikke n\u00f8dvendigvis er ensbetydende med forh\u00f8jet risiko for atherosklerose og hjerte-kar sygdom. P\u00e5 den baggrund anses det, at hvis karv\u00e6ggene er i topform g\u00f8r LDL-partikler ikke skade. Det er f\u00f8rst n\u00e5r de store karv\u00e6gges bekl\u00e6dning (endothelet) tager skade kan LDL-partikler tr\u00e6nge ind i v\u00e6ggen og initiere en inflammatorisk kaskade.<\/p>\n

Det er af denne \u00e5rsag, at jeg fandt en nylig artikel p\u00e5 Science Alert interessant: One protein is a better predictor of heart disease than cholesterol<\/a>. Artiklens titel tager nok lige munden lidt for fuld i forhold til aktuel viden, og selve artiklen skal ogs\u00e5 lige rettes til i forhold til nogle gr\u00e6nsev\u00e6rdier – men den indeholder en interessant pointe: at et m\u00e5l for kroppens niveau af inflammation kan v\u00e6re et vigtigt fingerpeg om ens risiko for at udvikle hjerte-kar sygdom.<\/p>\n

Blodets indhold af C-reaktivt protein (CRP) giver et generelt m\u00e5l for kroppens status i forhold til inflammation. Ved en virus- eller bakterieinfektion vil blodets indhold af CRP typisk stige kraftigt, som f\u00f8lge af leverens produktion af proteinet. Ved anden v\u00e6vsskade kan der ogs\u00e5 m\u00e5les for\u00f8get CRP.<\/p>\n

CRP-niveauet i blodet kan komme op over 200 mg\/L ved en akut bakterieinfektion, mens normalv\u00e6rdierne hos en sund og rask person vil v\u00e6re <1 mg\/L.<\/p>\n

Hvis man f\u00e5r foretaget en m\u00e5ling hos l\u00e6gen vil man normalt f\u00e5 oplyst, hvorvidt m\u00e5lingen ligger under en gr\u00e6nsev\u00e6rdi p\u00e5 3 mg\/L; hvis den er over dette kan det v\u00e6re et tegn p\u00e5 kronisk inflammation, og alts\u00e5 et r\u00f8dt flag i forhold til risiko for hjerte-kar sygdom.<\/p>\n

Faktisk ser det ud til, at American College of Cardiology<\/a> er begyndt at anse v\u00e6rdier allerede p\u00e5 >2 mg\/L som tegn p\u00e5 moderat \u00f8get risiko for hjerte-karsygdom. Foreningen angiver ogs\u00e5 at efte denne standard er pr\u00e6valensen for voksne med forh\u00f8jede v\u00e6rdier p\u00e5 30-35% i Europa og omkring 50% i USA.<\/p>\n

Det vil v\u00e6re interessant at se om almen l\u00e6gepraksis herhjemme \u00e6ndrer p\u00e5 gr\u00e6nsev\u00e6rdier og p\u00e5 at implementere CRP-m\u00e5linger i forbindelse med helbredsunders\u00f8gelser, der normalt omfatter et kig p\u00e5 kolesteroltallet.<\/p>\n","protected":false},"excerpt":{"rendered":"

Som det bl.a. kan l\u00e6ses i et tidligere indl\u00e6g her p\u00e5 bloggen s\u00e5 er der stadig diskussioner om, hvor betydende kolesteroltallet er i forhold til […]<\/a><\/p>\n<\/div>","protected":false},"author":1,"featured_media":5058,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[81],"tags":[829,128,323,114,250],"class_list":["post-5051","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-livsstil","tag-crp","tag-hjertesygdom","tag-inflammation","tag-kolesterol","tag-ldl"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"https:\/\/i0.wp.com\/seniorfitness.blog\/wp-content\/uploads\/2025\/12\/virus-5741636_1280.jpg?fit=1280%2C1011&ssl=1","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p8lpEz-1jt","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/5051","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=5051"}],"version-history":[{"count":7,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/5051\/revisions"}],"predecessor-version":[{"id":5059,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/posts\/5051\/revisions\/5059"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=\/wp\/v2\/media\/5058"}],"wp:attachment":[{"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=5051"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=5051"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/seniorfitness.blog\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=5051"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}